<sub id="t56hh"></sub>

    期刊文献+

    全国细菌耐药监测网2014—2019年临床分离非发酵革兰阴性杆菌耐药性变迁 认领

    Change in antimicrobial resistance of clinically isolated non-fermentative Gram-negative bacilli:surveillance report from China Antimicrobial Resistance Surveillance System in 2014-2019
    在线阅读 下载PDF
    收藏 分享 导出
    摘要 目的了解全国临床分离非发酵革兰阴性杆菌的耐药性变迁。方法按照全国细菌耐药监测技术方案要求开展耐药监测工作,参考美国临床实验室标准化协会(CLSI)标准对2014—2019年全国1000余家医院上报至全国细菌耐药监测网的非发酵革兰阴性杆菌的临床资料进行总结和分析。结果非发酵革兰阴性杆菌主要分离自呼吸道标本(痰和支气管肺泡灌洗液)、尿、脓液和血,分别占83.6%,6.5%,4.0%和3.6%。铜绿假单胞菌、鲍曼不动杆菌、嗜麦芽窄食单胞菌和洋葱伯克霍尔德菌占分离细菌的比率分别为8.8%,7.3%,2.1%和0.5%。铜绿假单胞菌对多粘菌素B、阿米卡星和庆大霉素的敏感率分别为96.9%~98.2%,89.1%~94.0%和80.1%~86.4%;对哌拉西林和氨曲南的敏感率分别为66.7%~72.8%和58.8%~62.4%;对其余抗菌药物的敏感率维持在70.4%~81.7%。鲍曼不动杆菌对多粘菌素B、阿米卡星和米诺环素的敏感率分别为96.2%~98.0%,51.0%~58.0%和59.4%~63.4%,对其余抗菌药物的敏感率为35.8%~50.0%。嗜麦芽窄食单胞菌对米诺环素、复方磺胺甲口恶唑和左氧氟沙星的敏感率分别为93.0%~95.3%,89.3%~91.4%和85.0%~86.6%,对替卡西林/克拉维酸和氯霉素的敏感率为37.4%~50.3%和46.6%~51.1%。洋葱伯克霍尔德菌对替卡西林/克拉维酸和氯霉素的敏感率分别为18.5%~37.0%和54.4%~62.2%,对其余抗菌药物的敏感率维持在64.7%~86.8%。耐碳青霉烯类铜绿假单胞菌检出率呈下降趋势,而耐碳青霉烯类鲍曼不动杆菌检出率呈现先上升后下降的变化趋势。结论非发酵革兰阴性杆菌对常用抗菌药物的敏感性无明显变化,耐碳青霉烯类铜绿假单胞菌和鲍曼不动杆菌检出率呈下降趋势。 Objective To understand the change in antimicrobial resistance of clinical non-fermentative Gram-negative bacilli in China.Methods Surveillance on antimicrobial resistance was carried out according to the requirements of China Antimicrobial Resistance Surveillance System(CARSS),referring to Clinical&Laboratory Stan-dards Institute(CLSI)standard,clinical data of non-fermentative Gram-negative bacilli reported to CARSS by more than 1000 hospitals in China from 2014 to 2019 were summarized and analyzed.Results Non-fermentative Gram-negative bacilli were mainly isolated from respiratory tract specimens(sputum and bronchoalveolar lavage fluid),urine,pus,and blood,accounting for 83.6%,6.5%,4.0%and 3.6%respectively.Isolation rates of Pseudomonas aeruginosa,Acinetobacter baumannii,Stenotrophomonas maltophilia,and Burkholderia cepacia were 8.8%,7.3%,2.1%and 0.5%respectively.Susceptibility rates of Pseudomonas aeruginosa to polymyxin B,amikacin and gentamicin were 96.9%-98.2%,89.1%-94.0%and 80.1%-86.4%respectively;susceptibility rates to piperacillin and aztreonam were 66.7%-72.8%and 58.8%-62.4%respectively;susceptibility rates to other antimicrobial agents were 70.4%-81.7%.Susceptibility rates of Acinetobacter baumannii to polymyxin B,amikacin and minocycline were 96.2%-98.0%,51.0%-58.0%and 59.4%-63.4%respectively,to other antimicrobial agents were 35.8%-50.0%.Susceptibility rates of Stenotrophomonas maltophilia to minocycline,sulfamethoxazole and levofloxacin were 93.0%-95.3%,89.3%-91.4%and 85.0%-86.6%respectively,susceptibility rates to ticarcillin/clavulanic acid and chloramphenicol were 37.4%-50.3%and 46.6%-51.1%respectively.Susceptibility rates of Burkholderia cepacia to ticarcillin/clavulanic acid and chloramphenicol were 18.5%-37.0%and 54.4%-62.2%respectively,susceptibility rates to other antimicrobial agents maintained 64.7%-86.8%.Isolation rate of carbapenem-resistant Pseudomonas aeruginosa decreased,while isolation rate of carbapenem-resis-tant Acinetobacter baumannii increased first and then decreased.Conclusio
    作者 无(China Antimicrobial Resistance Surveillance System)
    出处 《中国感染控制杂志》 CAS 北大核心 2021年第1期70-76,共7页 Chinese Journal of Infection Control
    关键词 非发酵革兰阴性杆菌 抗菌药物 耐药性 非发酵菌 铜绿假单胞菌 鲍曼不动杆菌 嗜麦芽窄食单胞菌 全国细菌耐药监测 non-fermentative Gram-negative bacillus antimicrobial agent antimicrobial resistance non-fermentative bacteria Pseudomonas aeruginosa Acinetobacter baumannii Stenotrophomonas maltophilia China Antimicrobial Resistance Surveillance System
    • 相关文献

    参考文献11

    • 1胡付品,郭燕,朱德妹,汪复,蒋晓飞,徐英春,张小江,张朝霞,季萍,谢轶,康梅,王传清,王爱敏,徐元宏,沈继录,孙自镛,陈中举,倪语星,孙景勇,褚云卓,田素飞,胡志东,李金,俞云松,林洁,单斌,杜艳,郭素芳,魏莲花,邹凤梅,张泓,王春,胡云建,艾效曼,卓超,苏丹虹,汪瑞忠,房华,俞碧霞,赵勇,龚萍,郭大文,赵金英,刘文恩,李艳明,金炎,邵春红,温开镇,张贻荣,徐雪松,鄢超,喻华,黄湘宁,王山梅,楚亚菲,张利侠,马娟,周树平,周艳,朱镭,孟晋华,董芳,郑红艳,沈瀚,周万青,贾伟,李刚,吴劲松,卢月梅,李继红,刘江山,廖龙凤,顾洪芹,姜琳,贺雯,薛顺虹,冯佼,窦睿,岳春雷.2018年CHINET中国细菌耐药性监测[J].中国感染与化疗杂志,2020,20(1):1-10. 被引量:67
    • 2张祎博,孙景勇,倪语星,俞云松,林洁,杨青,徐英春,张小江,孙自镛,陈中举,汪复,朱德妹,胡付品,蒋晓飞,王传清,王爱敏,卓超,苏丹虹,胡云建,艾效曼,黄文祥,贾蓓,张朝霞,季萍,张泓,孔菁,魏莲花,吴玲,徐元宏,沈继录,单斌,杜艳,胡志东,李金,谢轶,康梅,韩艳秋,郭素芳,褚云卓,田素飞.2005—2014年CHINET铜绿假单胞菌耐药性监测[J].中国感染与化疗杂志,2016,16(2):141-145. 被引量:125
    • 3胡付品,郭燕,朱德妹,汪复,蒋晓飞,徐英春,张小江,张朝霞,季萍,谢轶,康梅,王传清,王爱敏,徐元宏,沈继录,孙自镛,陈中举,倪语星,孙景勇,褚云卓,田素飞,胡志东,李金,俞云松,林洁,单斌,杜艳,郭素芳,魏莲花,邹凤梅,张泓,王春,胡云建,艾效曼,卓超,苏丹虹,汪瑞忠,房华,俞碧霞,赵勇,龚萍,郭大文,赵金英,刘文恩,李艳明,金炎,邵春红,温开镇,张贻荣,徐雪松,鄢超,喻华,黄湘宁,王山梅,楚亚菲,张利侠,马娟,周树平,周艳,朱镭,孟晋华,.2016年中国CHINET细菌耐药性监测[J].中国感染与化疗杂志,2017,17(5):481-491. 被引量:569
    • 4胡付品,朱德妹,汪复,蒋晓飞,徐英春,张小江,张朝霞,季萍,谢轶,康梅,王传清,王爱敏,徐元宏,沈继录,孙自镛,陈中举,倪语星,孙景勇,褚云卓,田素飞,胡志东,李金,俞云松,林洁,单斌,杜艳,韩艳秋,郭素芳,魏莲花,吴玲,张泓,孔菁,胡云建,艾效曼,卓超,苏丹虹.2014年CHINET中国细菌耐药性监测[J].中国感染与化疗杂志,2015,15(5):401-410. 被引量:689
    • 5胡付品,朱德妹,汪复,蒋晓飞,徐英春,张小江,张朝霞,季萍,谢轶,康梅,王传清,王爱敏,徐元宏,沈继录,孙自镛,陈中举,倪语星,孙景勇,褚云卓,田素飞,胡志东,李金,俞云松,林洁,单斌,杜艳,郭素芳,魏莲花,吴玲,张泓,王春,胡云建,艾效曼,卓超,苏丹虹,汪瑞忠,房华,俞碧霞,赵勇,龚萍.2015年CHINET细菌耐药性监测[J].中国感染与化疗杂志,2016,16(6):685-694. 被引量:370
    • 6胡付品,朱德妹,汪复,蒋晓飞,孙自镛,陈中举,胡志东,李金,谢轶,康梅,徐英春,张小江,张朝霞,季萍,王传清,王爱敏,倪语星,孙景勇,俞云松,林洁,储云卓,田素飞,徐元宏,沈继录,单斌,杜艳,卓超,苏丹虹,张泓,孔菁,魏莲花,吴玲,胡云建,艾效曼.2013年中国CHINET细菌耐药性监测[J].中国感染与化疗杂志,2014,14(5):365-374. 被引量:591
    • 7陈佰义,何礼贤,胡必杰,倪语星,邱海波,石岩,施毅,王辉,王明贵,杨毅,张菁,俞云松.中国鲍曼不动杆菌感染诊治与防控专家共识[J].中国医药科学,2012,2(8):3-8. 被引量:408
    • 8胡付品.2005--2014年CHINET中国细菌耐药性监测网5种重要临床分离菌的耐药性变迁[J].中国感染与化疗杂志,2017,17(1):93-99. 被引量:255
    • 9胡付品,朱德妹,汪复,蒋晓飞,杨青,徐英春,张小江,孙自镛,陈中举,王传清,王爱敏,倪语星,孙景勇,俞云松,林洁,单斌,杜艳,徐元宏,沈继录,张泓,孔菁,卓超,苏丹虹,张朝霞,季萍,胡云建,艾效曼,黄文祥,贾蓓,魏莲花,吴玲.2011年中国CHINET细菌耐药性监测[J].中国感染与化疗杂志,2012,12(5):321-329. 被引量:523
    • 10汪复,朱德妹,胡付品,蒋晓飞,胡志东,李全,孙自镛,陈中举,徐英春,张小江,王传清,王爱敏,倪语星,孙景勇,褚云卓,俞云松,林洁,徐元宏,沈继录,苏丹虹,卓超,魏莲花,吴玲,张朝霞,季萍,张泓,孔菁,胡云建,艾效曼,单斌,杜艳.2012年中国CHINET细菌耐药性监测[J].中国感染与化疗杂志,2013,13(5):321-330. 被引量:436

    二级参考文献117

    • 1王艳丽,黄茂,梅亚宁,殷凯生,.鲍曼不动杆菌对喹诺酮类药物的耐药机制研究[J].中国感染与化疗杂志,2008(4):266-270. 被引量:24
    • 2Peleg AY, Seifert H, Paterson DLAeinetobaeter baumannii: emergence of a successful pathogen. Clin Micmbiol Rev,2008,21 : 538-582. 被引量:1
    • 3Falagas ME, Koletsi PK, Bliziotis IA.The diversity of definitions of muhidrug-resistant(MDR) and pandrug-resistant (PDR) Aeinetohaeter bsumannli and Pseudomonas aeruginosa.J Med Microbiol, 2006,55: 1619-1629. 被引量:1
    • 4Paterson DL, Doi Y.A step closer to extreme drug resistance(XDR) in gram-negative bacilli.Clin Infect Dis,2007,45: 1179-1181. 被引量:1
    • 5Falagas ME, Karageorgopoulos DE.Pandrug resistance(PDR), extensive drug resistance(XDR), and muhidrug resistance(MDR) among Gram- negative bacilli: need for international harmonization in terminology.Clin Infect Dis, 2008,46: 1121-1122; author reply 1122. 被引量:1
    • 6Zhou H, Yang Q, Yu YS, et al. Clonal Spread of Imipenem-resistant Aeinetobaeter baumannii among different cities of China.J Clin Mierubiol, 2007,45 : 4054-4057. 被引量:1
    • 7Perez F, Hujer AM, Hujer KM, et al.Global challenge of multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother, 2007,51: 3471-3484. 被引量:1
    • 8Munoz-Price LS, Robert AW.Aclinetobaeter Infection.N Engl J Med,2008,358: 1271-1281. 被引量:1
    • 9Guardado AR, Blanco A, Asensi V, et al.Muhidrug-resistant Aeinetohaeter meningitis in neurosurgical patients with intraventricular catheters: assessment of different treatments. J Antimicrob Chemother,2008,61 : 908-913. 被引量:1
    • 10Lenie D, Alexandr N, Harald S.An increasing threat in hospitals: multidrug-resistant Aeinetobaeter baumannii.Nat Rev Microbiol, 2007,5: 939-951. 被引量:1

    共引文献3267

    202103读书月活动
    维普数据出版直通车
    今日学术
    投稿分析
    职称考试

    相关作者

    内容加载中请稍等...

    相关机构

    内容加载中请稍等...

    相关主题

    内容加载中请稍等...

    浏览历史

    内容加载中请稍等...
    ;
    使用帮助 返回顶部 意见反馈
    福利阁导航